Co-trimoxazole

Presciption Medicine
  • Effective Treatment for Serious Infections
  • Two ingredients (sulfamethoxazole and trimethoprim) for Powerful Action
  • Versatile and Accessible
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Product Information

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Medically Verified
Dr G Varbanov

Dr. Georgi Varbanov

General Medicine Doctor | UIN: 0400005105
Reviewed on: 7 April, 2025 View Profile

Dr. Georgi Varbanov is a family medicine physician dedicated to evidence-based care and disease prevention.

Co-trimoxazole is a combination antibiotic containing two active ingredients: sulfamethoxazole and trimethoprim. Together, they work synergistically to stop the growth of a wide range of bacteria. This dual-action makes co-trimoxazole especially effective in treating urinary tract infections (UTIs), including infections of the bladder and lower urinary tract.

It works by targeting two different steps in the bacterial production of folic acid, an essential substance for their growth and survival. By disrupting this process, co-trimoxazole not only kills the bacteria but also helps prevent the infection from spreading or recurring.

Co-trimoxazole is commonly prescribed for uncomplicated UTIs, including cystitis, especially when caused by bacteria like E. coli. It is often used in patients who may not respond to more commonly prescribed antibiotics or in regions where bacterial resistance patterns require broader coverage.

For urinary tract infections, the treatment is typically taken twice a day for a short period, often three to five days, depending on the severity and clinical response. Most patients begin to feel relief within the first few doses, with symptoms like painful urination, urgency, and lower abdominal discomfort gradually subsiding.

The medication is usually well tolerated, though some individuals may experience mild side effects such as nausea, rash, or increased sensitivity to sunlight. Rarely, more serious reactions can occur, so completing the prescribed course and staying hydrated during treatment is important.

Co-trimoxazole is not recommended during pregnancy or for patients with certain medical conditions unless prescribed under careful supervision.

General Information

What is [Product name]?

Co-trimoxazole is an antibiotic made up of two medicines, sulfamethoxazole and trimethoprim. These work together to treat bacterial infections by stopping bacteria from growing and spreading.

What is [Product name] used for?

It is used to treat various infections, including those of the lungs (like pneumonia), urinary tract, skin, intestines, and ears. It is also used to prevent infections in people with weakened immune systems.

How does [Product name] work in the body?

Co-trimoxazole stops bacteria from making folic acid, which they need to grow and survive. By blocking this process, it helps clear the infection.

What is the general recommended dosage for [Product name]?

Adults often take one or two tablets twice a day. The standard dose is typically 960 mg (160 mg trimethoprim + 800 mg sulfamethoxazole) twice daily, taken every 12 hours.

How long does it take to feel the effects of [Product name]?

You may start to feel better within a few days of starting treatment, but it’s important to complete the full course as prescribed.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed one and continue as usual. Do not take a double dose.

Safety & Side Effects

What are the possible side effects of [Product name]?

Common side effects include nausea, diarrhoea, headache, or skin rash. Rarely, it can cause serious reactions like difficulty breathing or severe skin rashes.

Can [Product name] cause allergies?

Yes, some people may be allergic to Co-trimoxazole. Symptoms include rash, itching, or swelling. Seek medical help if you notice any signs of an allergic reaction.

Can I combine [Product name] with other medications?

Co-trimoxazole can interact with some medicines like warfarin or methotrexate. Always inform your doctor about any medications you are taking.

Does [Product name] affect sleep or alertness?

It does not usually affect sleep or alertness. However, if you feel dizzy or tired after taking it, avoid driving or operating machinery.

Can I use this if I am pregnant or breastfeeding?

Co-trimoxazole should be used during pregnancy only if necessary and under medical supervision. It is generally safe during breastfeeding but should be used with caution.

Is [Product name] safe for long-term use?

Long-term use is safe for some conditions but requires regular monitoring by your doctor to check for potential side effects like blood disorders.

Is it safe to drink alcohol while using [Product name]?

It is best to avoid alcohol while taking this medication as it may increase side effects like nausea or dizziness.

Usage & Administration

How do I administer [Product name]?

Take it exactly as prescribed by your doctor, preferably with food to reduce stomach upset. Drink plenty of water during treatment.

What if I take too much [Product name]?

If you take too much, seek medical attention as soon as possible. Symptoms may include nausea, dizziness, or confusion.

Who should not take [Product name]?

It should not be taken by people allergic to its ingredients, those with severe liver or kidney problems, or babies under six weeks old. Pregnant women in their first trimester should avoid it, too.

How should I store [Product name] properly?

Store it in a cool, dry place away from direct sunlight and out of reach of children. Avoid storing it in damp areas like bathrooms.

Should I take [Product name] with food?

Yes, taking it with food can help reduce stomach upset, but it can also be taken on an empty stomach if needed.

Can I crush or dissolve the tablet in water?

If you have trouble swallowing tablets, ask your doctor or pharmacist at Trans to You before breaking or crushing them. Liquid forms may also be available.

Ordering & Delivery

How can I order [Product name] online?

To get Co-trimoxazole, fill out a medical form or book a video consult. After approval, your prescription is sent to the pharmacy for fast delivery.

Do I need a prescription for [Product name]?

Yes, Co-trimoxazole requires a prescription (RX) via a doctor. You can request the treatment via a doctor who is working with Transtoyou for purchase.

How fast is [Product name] delivered?

Co-trimoxazole is usually delivered in 1–2 business days after the prescription is received by the pharmacy.

Can I return [Product name] if I change my mind?

Once a prescription is issued and Co-trimoxazole is sent from the pharmacy, returns are not possible.

Product Documentation

This leaflet is provided for information purposes only. The official leaflet in the language of the country of delivery is supplied with the order.

EN

Co trimoxazole

120.80 KB Feb 2026 Tablet 480 mg - 30 pieces
Informational leaflet with dosage instructions and safety information.
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