Spironolactone is a potassium-sparing diuretic used to treat conditions such as high blood pressure, fluid retention, and certain hormone-sensitive disorders. It functions by blocking aldosterone, a hormone that promotes sodium and water retention, which helps reduce fluid buildup and lower blood pressure.<\/p>\n
In addition to its cardiovascular uses, spironolactone may be included in feminizing hormone therapy, often for transgender women and non-binary individuals. It acts as an anti-androgen, potentially reducing the effects of testosterone on the skin, hair, and body over time. Reported effects may include decreased facial\/body hair, less scalp hair thinning, and softer skin, although changes can vary significantly by individual.<\/p>\n
Spironolactone is usually taken orally once or twice per day. Dosage is personalized based on medical condition, lab results, and treatment goals. It is often combined with estrogen therapy in gender-affirming care. Monitoring of kidney function and electrolytes is recommended throughout treatment.<\/p>\n
Side effects may include frequent urination, dizziness, breast tenderness, and elevated potassium levels. Spironolactone is not recommended for individuals with severe kidney impairment, high potassium, or Addison\u2019s disease.<\/p>\n","protected":false},"excerpt":{"rendered":"