Zyban

Presciption Medicine
  • Non-nicotine stop-smoking aid
  • Reduces cravings and withdrawal
  • Begin 1 week before quit date
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Product Information

Better health begins with the right choices.

Medically Verified
Dr. Cosmin Alexandru | Expert Transtoyou

Dr. Cosmin Alexandru

General Medicine Doctor | CUIM: 2791492305
Reviewed on: 7 June, 2025 View Profile

Dr. Cosmin Alexandru has 20+ years in emergency and family medicine, now serving at County Clinic Hospital Sibiu.

Zyban is a prescription medication used to help people stop smoking. It contains bupropion, a compound that was originally developed as an antidepressant but was later found to significantly reduce nicotine cravings and withdrawal symptoms. Unlike nicotine replacement therapies, Zyban does not contain nicotine. Instead, it works by altering the levels of certain neurotransmitters in the brain, particularly dopamine and norepinephrine, which are involved in addiction and mood regulation.

Zyban is taken as a tablet, typically started one to two weeks before the planned quit date. This allows the medication to build up in the system and begin reducing cravings by the time smoking stops. Treatment usually continues for 7 to 12 weeks, depending on individual progress and doctor’s recommendations.

Zyban is especially helpful for individuals who have tried other stop-smoking aids without success or for those who prefer a non-nicotine-based approach. When used alongside behavioral support, Zyban has been shown to significantly increase the chances of quitting successfully.

Side effects may include dry mouth, insomnia, headache, or changes in appetite. It is important not to exceed the prescribed dose, as higher doses can increase the risk of seizures. Zyban should not be used in combination with other medications that also affect serotonin or in people with a history of seizures or eating disorders.

General Information

What is [Product name]?

Zyban is a prescription medication that contains bupropion, used to help people quit smoking. It does not contain nicotine and works by affecting brain chemicals related to addiction and cravings. 

What is [Product name] used for?

Zyban is used to support smoking cessation by reducing nicotine cravings and withdrawal symptoms. It is often prescribed when other methods have not been effective. 

How does [Product name] work in the body?

Zyban influences the levels of dopamine and norepinephrine in the brain, two neurotransmitters involved in reward and addiction. This helps reduce the desire to smoke and manage mood changes during withdrawal. 

What is the general recommended dosage for [Product name]?

Typically, treatment begins with one tablet per day for the first three days, followed by two doses per day, spaced at least eight hours apart. It is started one to two weeks before the quit date. 

How long does it take to feel the effects of [Product name]?

It takes about one week for the medication to reach effective levels. Cravings and withdrawal symptoms often lessen within the first two weeks of use. 

What should I do if I forget a dose?

If you miss a dose, skip it and take your next dose at the scheduled time. Never double up to make up for a missed tablet.

Safety & Side Effects

What are the possible side effects of [Product name]?

Common side effects include dry mouth, insomnia, restlessness, and headache. Rarely, it may increase the risk of seizures, especially if taken in high doses or by individuals with specific risk factors. 

What are the contraindications of [Product name]?

It should not be used by people with a history of seizures, eating disorders, severe liver disease, or those taking monoamine oxidase inhibitors (MAOIs). 

Can I combine [Product name] with other medications?

You must inform your doctor of all medications you are taking. Some drug interactions can increase the risk of side effects or reduce effectiveness. 

Can I use this if I am pregnant or breastfeeding?

Use during pregnancy or breastfeeding should be carefully evaluated by a healthcare provider. Zyban is only recommended when the benefits outweigh the risks. 

Is it safe to drink alcohol while using [Product name]?

Alcohol should be limited or avoided during Zyban treatment, as it can increase the risk of seizures and other side effects. 

Usage & Administration

How do I administer [Product name]?

Take the tablets by mouth with water. Do not crush or chew. Take doses at least eight hours apart to reduce side effect risk. 

How should I store [Product name] properly?

Store at room temperature in a dry place. Keep the medication in its original packaging and out of reach of children. 

Should I take [Product name] with food?

Zyban can be taken with or without food. If it causes stomach upset, taking it with a light meal may help. 

Can I crush or dissolve the tablet in water?

No, Zyban tablets should be swallowed whole. Crushing or chewing may increase the risk of side effects. 

Ordering & Delivery

How can I order [Product name] online?

To get [Product name], fill out a medical form or book a video consult with a doctor via Transtoyou. After approval, your prescription is sent to the pharmacy for fast delivery.

Do I need a prescription for [Product name]?

[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.

How fast is [Product name] delivered?

After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.

Can I return [Product name] if I change my mind?

For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped. 

Product Documentation

All Variants

Select a variant to see specific documentation. Leaflets are provided for information purposes only. The official leaflet in the language of the country of delivery is supplied with the order.

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Zyban

128.65 KB Mar 2026 Multi-variant
Informational leaflet with dosage instructions and safety information.
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